Pairing Cannabis Effects with Art, Animals, and Zen in One of Santa Ana’s Most Unexpected Corners
The Zoo District may not be the first place that comes to mind when you think of Santa Ana, but it’s a gem. Experience multicultural munchies, vibrant public art, and a charming local zoo in this under-the-radar neighborhood that’s ideal for travelers craving a blend of creativity and nature. With curated cannabis effect pairings to match the mood of each moment, here’s how to make the most of a weekend elevated itinerary in Santa Ana’s Zoo District.
Day 1: Chill Curiosity + Colorful Inspiration
Morning – Wake, Bake, and Brunch
Start your day with a zesty citrus-smelling cannabis cultivar or a balanced 1:1 THC:CBD edible that can help spark focus and curiosity. Find what you need with a quick visit to Green Mart, a locally-loved dispensary not far from the Zoo. Its neighborhood feel and knowledgeable budtenders make it a convenient stop for travelers.
Grab a coffee and breakfast sandwich from Huskins Coffee for an energizing and welcoming start. Their cozy vibe and delicious espresso drinks set the tone for a weekend of exploring.
Late Morning – Santa Ana Zoo
Let your day unfold amongst the animals at Santa Ana Zoo, a sweet local institution known for its commitment to South American wildlife and playful monkey exhibits. With your buzz still active, wander through lush habitats and colorful aviaries, letting your elevated senses engage fully with the sounds and sights of nature. Pro tip: check the calendar of events for engaging activations and special exhibits before you head out.
Afternoon – Art Walk with a Lift
Head downtown to the Grand Central Art Center, a contemporary art space showcasing thought-provoking installations and exhibits from emerging and established artists. This is a great time to enjoy a floral-scented cultivar, which many report can help induce a creative flow state perfect for visual exploration.
Then, let the streets guide you through Santa Ana’s vibrant public art scene, where alleys and buildings bloom with murals, color, and graffiti. Don’t miss the mural-lined Callejon del Beso, known as the "Alley of the Kiss," a must-see for anyone craving visual stimulation and cultural flavor. For cannabis-themed street art highlights, check out the 420 Art Crawl guide.
Evening – Pizza Night
Next, take your appetite to Bari Pasta & Pizza, where rustic Italian comfort food hits the spot after a long day of walking and exploring. Order the margherita pizza or housemade pasta, or try their unique signature “pizza skulls,” and let your evening unwind. If you’re not quite ready to tuck in after dinner, explore some of Santa Ana’s lively nightlife options.
Where to Stay
Book a suite at the Sonesta Simply Suites Orange County for a relaxed, homey base near the Zoo District. Or go for the reliable comfort of the Holiday Inn Express & Suites (pictured). Both provide easy access to your weekend stops.
Day 2: Deep Relaxation + Spa Serenity
Morning – Shopping + Brunch
Today is all about deep relaxation. Start with a morning stop at Ashe Society, a woman-owned dispensary known for its beautifully designed space and powerful Kobe Bryant tribute mural. Their thoughtful product selection includes wellness-focused edibles and topicals. Ask your budtender to guide you to a sweet fruity or floral-smelling cultivar or products that balance THC with CBD and CBN to help set the mood for a calm and soothing spa day.
After stocking up, head to Santa Ana Brunch Club for an indulgent brunch. Their fun, vibrant vibe pairs beautifully with a restful, body-heavy high. Grab the chilaquiles or their signature French toast and settle in.
Afternoon – Spa Escape
Float into Montanya Spa, a serene oasis known for luxury massages, facials, and full-body treatments. This is your chance to fully lean into the cannabis and wellness connection. If you picked up a soothing topical from Ashe Society, ask the spa team if you can incorporate it into your massage for a personalized touch.
Afterwards, you can lounge in their zen relaxation area or take a slow stroll through nearby neighborhoods to decompress. This is what cannabis-enhanced travel is all about—intentional stillness, awareness, and joy.
Evening – Sensory Finale at Planet 13
Wrap your stay in Santa Ana with a visit to Planet 13, one of the largest cannabis retail experiences in the U.S. It’s more than a dispensary—it’s a spectacle. Explore interactive art and curated product displays designed to engage all your senses. Check their events calendar before your trip to see if any exciting events are happening.
Then head nearby for dinner at Avila's El Ranchito (right), a family-owned favorite where you can feast on carne asada, shrimp tacos, and traditional margaritas. Or for something cozier, wind down with a gourmet Japanese meal at Kaizen Shabu (left), where hot pot brings warmth and community to the table.
Your Cannabis-Enhanced Neighborhood Escape
Santa Ana’s Zoo District blends culture, calm, and creativity in a way few neighborhoods do. Whether you’re soaking in art, enjoying the company of capuchins, or letting go in a warm massage room, there’s something here for every kind of cannabis traveler.
Explore Santa Ana’s cannabis-friendly spots and plan your next lifted journey at Travel Santa Ana’s Cannabis Guide.
